1. [n]  impudent aggressiveness; "I couldn't believe her boldness"; "he had the effrontery to question my honesty"
2. [n]  the courage to carry on; "he kept fighting on pure spunk"; "you haven't got the heart for baseball"
3. [n]  any bundle of nerve fibers running to various organs and tissues of the body
4. [v]  get ready for something difficult or unpleasant

Nerve
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1. \Nerve\, n. [OE. nerfe, F. nerf, L. nervus, akin to Gr. ?
   sinew, nerve; cf. ? string, bowstring; perh. akin to E.
   needle. Cf. {Neuralgia}.]
   1. (Anat.) One of the whitish and elastic bundles of fibers,
      with the accompanying tissues, which transmit nervous
      impulses between nerve centers and various parts of the
      animal body.
   Note: An ordinary nerve is made up of several bundles of
         nerve fibers, each bundle inclosed in a special sheath
         (the perineurium) and all bound together in a
         connective tissue sheath and framework (the epineurium)
         containing blood vessels and lymphatics.
   2. A sinew or a tendon. --Pope.
   3. Physical force or steadiness; muscular power and control;
      constitutional vigor.
            he led me on to mightiest deeds, Above the nerve of
            mortal arm.                           --Milton.
   4. Steadiness and firmness of mind; self-command in personal
      danger, or under suffering; unshaken courage and
      endurance; coolness; pluck; resolution.
   5. Audacity; assurance. [Slang]
   6. (Bot.) One of the principal fibrovascular bundles or ribs
      of a leaf, especially when these extend straight from the
      base or the midrib of the leaf.
   7. (Zo["o]l.) One of the nervures, or veins, in the wings of
      insects.
   {Nerve cell} (Anat.), one of the nucleated cells with which
      nerve fibers are connected; a ganglion cell.
   {Nerve fiber} (Anat.), one of the fibers of which nerves are
      made up. These fibers are either {medullated} or
      {nonmedullated}. in both kinds the essential part is the
      translucent threadlike axis cylinder which is continuous
      the whole length of the fiber.
   {Nerve stretching} (Med.), the operation of stretching a
      nerve in order to remedy diseases such as tetanus, which
      are supposed to be influenced by the condition of the
      nerve or its connections.
   

2. \Nerve\, v. t. [imp. & p. p. {Nerved}; p. pr. & vb. n.
   {Nerving}.]
   To give strength or vigor to; to supply with force; as, fear
   nerved his arm.