\Hec"a*tomb\, n. [L. hecatombe, Gr. ?; ? hundred + ? ox: cf. F. h['e]catombe.] (Antiq.) A sacrifice of a hundred oxen or cattle at the same time; hence, the sacrifice or slaughter of any large number of victims. Slaughtered hecatombs around them bleed. --Addison. More than a human hecatomb. --Byron.