\In*ef"fi*ca*cy\, n. [L. inefficacia. See {In-} not, and {Efficacy}.] Want of power to produce the desired or proper effect; inefficiency; ineffectualness; futility; uselessness; fruitlessness; as, the inefficacy of medicines or means. The seeming inefficacy of censures. --Bp. Hall. The inefficacy was soon proved, like that of many similar medicines. --James Gregory.