\Dis*peo"ple\, v. t. [imp. & p. p. {Dispeopled}; p. pr. & vb. n. {Dispeopling}.] [Pref. dis- + people: cf. F. d['e]peupler.] To deprive of inhabitants; to depopulate. Leave the land dispeopled and desolate. --Sir T. More. A certain island long before dispeopled . . . by sea rivers. --Milton.