\Ca*lum"ba\, n. [from kalumb, its native name in Mozambique.] (Med.) The root of a plant ({Jateorrhiza Calumba}, and probably {Cocculus palmatus}), indigenous in Mozambique. It has an unpleasantly bitter taste, and is used as a tonic and antiseptic. [Written also {colombo}, {columbo}, and {calombo}.] {American calumba}, the {Frasera Carolinensis}, also called {American gentian}. Its root has been used in medicine as bitter tonic in place of calumba.