\Be*twixt"\, prep. [OE. betwix, bitwix, rarely bitwixt, AS. betweox, betweohs, betweoh, betw[=i]h; pref. be- by + a form fr. AS. tw[=a] two. See {Between}.] 1. In the space which separates; between. From betwixt two aged oaks. --Milton. 2. From one to another of; mutually affecting. There was some speech of marriage Betwixt myself and her. --Shak. {Betwixt and between}, in a midway position; so-so; neither one thing nor the other. [Colloq.]