ALPHA FETOPROTEIN - Definition

WordNet Dictionary

	Definition:	[n] an abnormally large amount of this fetoprotein in the fetus can signal an abnormality of the neural tube (as spina bifida or anencephaly)

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	Synonyms:	AFP, alpha foetoprotein

	See Also:	fetoprotein, foetoprotein

Medical Dictionary

	Definition:	A protein produced by fetal tissues and some types of cancers in adults. Usually undetectable in the blood of healthy nonpregnant adults.

Biology Dictionary

	Definition:	This is a protein the blood level of which is measured by laboratory methods. Its level is elevated in the mother's blood when there are fetal spinal cord defects (anencephaly, myelomeningocele), threatened abortion, twin gestation, and abruptio placentae. The AFP screening test for the mother's blood is usually conducted at 16 - 18 weeks of pregnancy. AFP level in the amniotic fluid obtained in amniocentesis is measured to identify abnormal fetal development. In humans, AFP is a useful marker for the diagnosis and assessment of the tumors of the testis (teratocarcinoma and embryonal carcinoma). AFP is also elevated in patients with primary liver cancer (hepatocellular carcinoma) and in women with some types of germ cell ovarian tumors. Normal range: less than 40 micrograms per liter. The fetal equivalent of albumin.