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Meaning of SIMULATED ANNEALING

Computing Dictionary
 
 Definition: 

A technique which can be applied to any minimisation or learning process based on successive update steps (either random or deterministic) where the update step length is proportional to an arbitrarily set parameter which can play the role of a temperature. Then, in analogy with the annealing of metals, the temperature is made high in the early stages of the process for faster minimisation or learning, then is reduced for greater stability.

 
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Biology Dictionary
 
 Definition: In the biosciences, this refers to using computers to model how complementary strands of DNA or RNA will link via hydrogen bonds to form a double-stranded molecule, or how a protein sequence will fold up and make hydrogen bonds with itself to form a more convoluted molecule.

For more information, visit Molecular Origami.

 

 

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