Meaning of SICKLE-CELL ANEMIA

WordNet Dictionary
	Definition:		[n]  a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape
	Websites:
	Synonyms:		crescent-cell anaemia, crescent-cell anemia, drepanocytic anaemia, drepanocytic anemia, sickle-cell anaemia, sickle-cell disease
	See Also:		anaemia, anemia, monogenic disease, monogenic disorder
Medical Dictionary
	Definition:		The most common form of sickle cell disease. Other types of sickle cell disease include hemoglobin SC disease and sickle beta-thalassemia; there are also other, less common types of sickle cell disease.
	Websites:
Biology Dictionary
	Definition:		A disease found almost exclusively in people of African ethnic descent which is characterized by the presence of defective hemoglobin molecules that cause red blood cells to be malformed, often taking on a sickle shape. The protein defect is caused by a homozygous allele that codes for the Beta chain of hemoglobin (the genetic defect causes a valine to be inserted at position 6 instead of a glutamine; in low oxygen conditions, the malformed hemoglobins link into polymers that damage the cell's membrane and cause it to take on the sickle shape). The malformed cells can't carry oxygen properly, and can tend to clog capillaries and small veins. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities.
	Websites:
Glossary
	Definition:		a disorder in individuals homozygous for hemoglobin S in which red blood cells will develop into a sickle shape that, in turn, will clog capillaries, resulting in anemia, heart failure, etc.
	Websites: