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Meaning of PERNICIOUS ANEMIA

Pronunciation:  pur'nishus u'neemeeu

WordNet Dictionary
 
 Definition: [n]  a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)
 
 Websites: 
 
 Synonyms: malignant anaemia, malignant anemia, pernicious anaemia
 
 See Also: anaemia, anemia, megaloblastic anaemia, megaloblastic anemia, metaplastic anaemia, metaplastic anemia

 

 

Medical Dictionary
 
 Definition: 
  1. A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12.
  2. A particular form of anemia caused by inability to absorb vitamin B12 from the intestinal tract.
 
Biology Dictionary
 
 Definition: This is anemia due to the production of an autoantibody against the parietal cells and a blocking antibody that blocks the binding of vitamin B12 to the intrinsic factor. A third autoantibody blocks the absorption of the B12-intrinsic factor complex . Megaloblastic anemia results from the lack of B12.
 

 

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