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Meaning of NUCLEASE

Pronunciation:  'nooklee`eys

WordNet Dictionary
 
 Definition: [n]  general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
 
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 See Also: endonuclease, enzyme, exonuclease

 

 

Biology Dictionary
 
 Definition: An enzyme that breaks down the linkages (phosphodiesters) between nucleic acids in a nucleotide chain.
 
Glossary
 
 Definition: A class of enzymes that degrades DNA and/or RNA molecules by cleaving the phosphodiester bonds that link adjacent nucleotides. In deoxyribonuclease (DNase), the substrate is DNA. In endonuclease, it cleaves at internal sites in the substrate molecule. Exonuclease progressively cleaves from the end of the substrate molecule. In ribonuclease (RNase), the substrate is RNA. In the S1 nuclease, the substrate is single-stranded DNA or RNA.
 

 

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