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saccharin ---> secondary diabetessecondary tumor ---> short gut syndromeshunt ---> soft-tissuesolid tumor ---> splenic flexure syndromesplenic sequestration crisis ---> stage ii adrenocortical cancerstage ii anal cancer ---> stage iii laryngeal cancerstage iii lip and oral cavity cancer ---> stage iv wilms' tumorstage iva pancreatic cancer ---> stressstress fracture ---> suppositorysuppuration ---> systolic pressure