\Mo*noc"e*ros\, n. [L., fr. Gr. ?; mo`nos alone, single + ke`ras horn.] 1. A one-horned creature; a unicorn; a sea monster with one horn. Mighty monoceroses with immeasured tails. --Spenser. 2. (Astron.) The Unicorn, a constellation situated to the east Orion.