[n] congenital condition in which the colon does not have the normal network of nerves; there is little urge to defecate so the feces accumulate and cause megacolon
Hirschsprung's disease is a disorder of the newborn characterized by failure to pass the meconium; this results in abdominal distention. It is due to the absence of ganglion cells in the mucosal and muscular layers of the colon. There is a familial pattern.